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I-Bresis™
Hybrid Iontophoresis System

With the power of traditional dose controllers, but the flexibility of a patch, the I-Bresis iontophoresis system makes it easy to deliver the optimum dose of medicine to your patient while freeing you up to provide therapy.

This efficient, needle-free system takes the pain out of drug delivery for both the patient and the therapist.

What makes up the I-Bresis system?

The I-Bresis system comprises three components:

  • the Dose Controller, which attaches to and activates the patch
  • Patches, which are battery-powered and can be used with or without the Dose Controller
  • the Charging Station, which keeps the Dose Controllers charged between uses.

How does it work?

The system enables three modes of drug delivery:


I-Bresis™ Mode
I-Bresis&tm; The Dose Controller, attached to the Patch, delivers current at 3 mA to the Patch for three minutes for a Skin Conductivity Enhancement (SCE). This is followed by the patient wearing the Patch for 1-2 hours, resulting in a 40-80 mA-min treatment respectively.

Standard Mode
The Dose Controller delivers current at 2, 3 or 4 mA to the Patch for 10-20 minutes, resulting in a 40 mA-min treatment. For an 80 mA-minute treatment, repeat the process.

Patch-Only Mode
The Patch delivers low-level current over 2-4 hours, resulting in an approximate 40-80 mA-min treatment respectively.


I-Bresis vs. Traditional “Wired” Iontophoresis

The biggest advantage that I-Bresis offers the clinician and the patient alike is time-savings. A traditional iontophoresis treatment – in which the patient sits and receives medicine via transdermal electrodes connected by wires to a current generator – can take 15 to 20 minutes. But if the patient has already been in the clinic for an hour to receive other therapies, that extra time can create a time burden. A wired system also requires the clinician to monitor the process and disconnect the device once the drug has been delivered, which takes him or her away from treating other patients.

The wireless I-Bresis system frees up both the clinician and the patient. The wearable transdermal patch electrodes can be placed on the patient and activated, after which the patient can leave.* Later, once the drug-delivery time period has elapsed, the patient removes and disposes of the patch.

* When I-Bresis or Patch-Only modes are used. In Standard mode, the Dose Controller remains connected to the Patch, requiring the patient to remain, but still requiring less involvement from the therapist.